The main purpose of this assignment is to provide a better understanding of the nutritional supplements, and its impact on reducing disease attributed go oxidant stress. The oxidative Stress is generally an imbalance in the production of free radicals and the body's capability to neutralize and detoxify their harmful effects through neutralization by antioxidants. However, the paper will be discussing the oxidant stress and the disease that leads to a human body. The paper will also represent the pros and cons of the Stress and the overall research that has been analyzed throughout.
Oxidative Stress refers to the disparity amid the complimentary radicals and antioxidants in your body. The free radicals are said to be the molecules that contain molecules along with an irregular number of electrons. Such odd numbers permit them to react with the molecules easily. Such radicals can lead to numerous chemical reactions in a human body, due to their reactions to the molecules. Therefore, such reactions are known as oxidation. It has some benefits as well as some harmful effects (Bache et al., 2016).
Oxidation is a standard and essential method that exists in the human body. However, Oxidation Stress, on the other side, takes place at the point of time where some sort of imbalance in the radical activity and antioxidant activity. Therefore, free radicals can enable the body to fight off the pathogens, which causes various infections in the human body. Nevertheless, in case there are more of the free radicals present than can be kept in balance by antioxidants, it can lead to some severe damages to fatty tissue, DNA, and proteins in a human body to some extent. Damages and harmful effects in those components of a human body can cause a huge number of diseases over time. The diseases caused by oxidative Stress are diabetes, solidification of the blood vessel, inflammatory conditions, hypertension, an increase in the blood pressure, disease related to heart, cancer, ageing, neurodegenerative disease, etc. (Kreis et al., 2019).
According to the research and study (Wang et al., 2017), Oxidative Stress has been analyzed to be connected with the changes in ROS, RNS, and nitric oxide (NO) indicating directions. In contrast, bioavailable NO is reduced and ROS and RNS production is upgraded. Inflammatory reactions persuade the directions of oxidation stress, and succeeding mitochondrial metabolic methods creates largely reactive free radical molecules. ROS and RNS are composed of extremely active moieties that can respond with some alternative substrates (Zheng et al., 2016).
Mainly, the body’s cell reproduced free radicals while the procedure of normal metabolic. Nevertheless, body cells manufacture antioxidants that counteract some free radicals. Normally, a human body can preserve a balance between antioxidants and free radicals (Nielson et al., 2017). Various components are associated with oxidative stress and excess free radical production. Such factors are diet, the standard of living, specific situation, factors related to the environment such as pollution and radiation. The immune reaction that naturally exists in a human body can also temporarily activate some oxidative stress. Such oxidation stress leads to gentle tenderness that exits the body after the immunity fights off the respective infection or heals the injury. Components that may upsurge an individual's risk of oxidative Stress for long-term basis are fatness, high-fat diets, radiation, smoking, and consumption of alcohol, some medicines, environmental factors, and exposure to pesticides (Arimoto-Matsuzaki, Saito and Takekawa, 2016).
It is a fact that a human body needs free radicals and antioxidants and is very important for survival. However, excessive of such radicals and antioxidants may cause severe health problems in a human body. Therefore, some preventive measures can avoid a human body from facing such kinds of health issues.
• A person needs to adopt a healthy diet, which means having a diet that is less of fat and sugar. Having a balanced diet can keep a person healthy on a normal basis and therefore, can fight off the infections caused by the excess of free radicals in their body. For a balanced diet, people can make increased use of fruits and vegetables. It will keep the body away from facing oxidation stress.
• The most important measure that a person should be concerned about is less consumption of fatty foods and food with high sugar. Consumption of processed food will lead a human body to be unhealthy from within, which will create heavy chances of infection and disease. Therefore, every individual must be concerned about it.
• Body Exercise regularly is essential to fight off the diseases caused by oxidation stress in the body. It, however, enables the body to deal with minor diseases. In general words, body exercise will keep a person fit, which will automatically help them to fight off the infection from the body.
• Quit smoking and alcohol consumption because it will lead a human body to cause many severe health issues that can also lead to death. Therefore, people should not consume any of it, as it will not let the person fight the infection or diseases caused by the oxidation stress. Hence the person will have to face severe diseases.
As per the overall review of the assignment, it can be said that Oxidative Stress and free radicals are normally said to be harmful to human health. Numerous researches are studies have determined that the free radical offers to beginning and sequence of various pathologies, ranging from CVD to cancer. Therefore, the paper has described oxidation stress and its impact on the human body. It has been analyzed that the oxidation stress is the most harmful component that leads to various severe disease in a body. Therefore, at last, the paper also has explained about the prevention process of the same that would avoid an individual from having some heavy health issues.
Arimoto-Matsuzaki, K., Saito, H. and Takekawa, M., 2016. TIA1 oxidation inhibits stress granule assembly and sensitizes cells to stress-induced apoptosis. Nature communications, 7(1), pp.1-10.
Bache, M.R., O’Hanlon, J., Child, D.J. and Hardy, M.C., 2016. High temperature fatigue behaviour in an advanced nickel based superalloy: The effects of oxidation and stress relaxation at notches. Theoretical and Applied Fracture Mechanics, 84, pp.64-71.
Kreis, P., Gallrein, C., Rojas-Puente, E., Mack, T.G., Kroon, C., Dinkel, V., Willmes, C., Murk, K., Schuman, E.M., Kirstein, J. and Eickholt, B.J., 2019. ATM phosphorylation of the actin-binding protein drebrin controls oxidation stress-resistance in mammalian neurons and C. elegans. Nature communications, 10(1), pp.1-13.
Nielson, J.R., Fredrickson, E.K., Waller, T.C., Rendón, O.Z., Schubert, H.L., Lin, Z., Hill, C.P. and Rutter, J., 2017. Sterol oxidation mediates stress-responsive Vms1 translocation to mitochondria. Molecular cell, 68(4), pp.673-685.
Wang, J., Liu, S., Li, C., Wang, T., Zhang, P. and Chen, K., 2017. PnLRR-RLK27, a novel leucine-rich repeats receptor-like protein kinase from the Antarctic moss Pohlia nutans, positively regulates salinity and oxidation-stress tolerance. PLoS One, 12(2), p.e0172869.
Zheng, Y., Qu, J., Qiu, L., Fan, L., Meng, S., Song, C., Bing, X. and Chen, J., 2016. Effect of 17α-methyltestosterone (MT) on oxidation stress in the liver of juvenile GIFT tilapia, Oreochromis niloticus. Springerplus, 5(1), pp.1-8.
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